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Activating NOTCH and AKT gene may trigger cholangiocarcinoma
A rare type of cancer thought to derive from cells in the bile ducts of the liver may actually develop when one type of liver cell morphs into a totally different type, a process scientists used to consider all but impossible. UCSF researchers triggered this kind of cellular transformation-and caused tumors to form in mice-by activating just two genes. Their discovery suggests that drugs that are able to target those genes may provide a way to treat the deadly cancer, known as cholangiocarcinoma. It also shows, yet again, how the process of scientific discovery involves serendipity as well as skill.The study appears as an advanced online publication July 16, 2012 in the Journal of Clinical Investigation and will appear later in the August print edition.Comments (0) -
Dendritic Cell Therapy - Cancer Vaccine Clinical Trial in Buffalo NY
BUFFALO (WABC) -- People who fear cancer and those who are fighting are hopeful today from news coming from Buffalo.It's the announcement of a new clinical trial to test a vaccine that many prevent cancer from recurring.Researchers at the Roswell Park Cancer Center in Buffalo are attempting to harness a person's own immune system to destroy cancer cells.The vaccine will focus on cells of the immune system known as Dendritic cells.Comments (0) -
Diabetes Drug Metformin May Protect From Liver Cancer
Metformin, a oral drug prescribed for patients with type 2 diabetes, may protect against liver cancer, finds a study:Comments (0) -
Universal Cancer Vaccine NOW in clinical trial with excellent results
Hang in there folks! I am hearing a lot of great news lately about breakthrough discoveries....Keep on fighting the good fight!!! Here is a recent article about a "universal cancer vaccine" (developed in Israel) that is in clinical trial NOW!Comments (0) -
The Cholangiocarcinoma Foundation
Founded in 2006, the Cholangiocarcinoma Foundation provides help for patients and caregivers, advocates for those afflicted and educates those who do not understand.The non-profit 501(c)(3) foundation is run solely by volunteers having lost a loved one to cholangiocarcinoma or suffering from cholangiocarcinoma and surviving.
Our mission is to find a cure and improve the quality of life for those affected by bile duct cancer. As our reach continues to expand, we examine ways to improve diagnosis and early detection and advance therapies for prolonging life.
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To the Cancer Patient: Natural Cures vs. Traditional - Dr Tim O’Shea
Most legitimate researchers know that in the normal body hundreds of potential cancer cells appear every day. These defective mutated cells are usually destroyed by the normal immune system and never cause a problem. Cancer only gets started when a failing immune system begins to allow abnormal cells to slip by without triggering an attack on them.Other cancer cells do not trigger the immune response at all because the DNA is not that different from normal cells. Then they begin to proliferate, having lost the ability to specialize. That’s what cancer is. Runaway tissue.
So looking at it this way, a tumor is a symptom, not a problem. A symptom of a failing immune system....
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Saffron Takes on Cancer
We also saw a good article about saffron (the spice that is used in lots or Spanish and mediterrean cooking):
http://www.sciencenews.org/view/generic/id/333911/title/Saffron_takes_on_cancer
Six out of eight rats on the placebo got liver cancer from liver cancer causing drugs, while only 4 out of 24 on saffron got cancer.
Here is another articles that talks about it. Sounds like another natural tool along with turmeric.
http://azer.com/aiweb/categories/magazine/ai142_folder/142_articles/142_saffron.html
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Dr. Aldino Pierotti
Dr. Pierotti did extensive blood work and testing on Bruce to look for underlying issues with his immune system. Dr. Pierotti is located in Pittsburgh, PA.Comments (0) -
Dr. Stan Burzynski
Dr. Stan Burzynski is located in Houston. He is using antineoplastons to fight and even “cure” cancer in some cases. These are naturally occurring peptides that are missing in people with cancer. He believes that these peptides turn on the genes that help our bodies fight cancer. It sounds similar to the hormone replacement therapy in that it just replaces natural things in your body that are supposed to be there anyway.Comments (0) -
Dr. James Forsythe
Dr. James Forsythe is based in Reno, NV. He does both standard of care and alternative treatments.Comments (0) -
Dr. Nicholas Gonzales
Dr. Nicholas Gonzales is based in New York. He is using pancreatic enzymes in a manner that is similar to the use of hormones and peptides. They find what is missing and add it back.Comments (0) -
Scottsdale Healthcare - Clinical Trials
Arizona lab providing clinical trials. Of note is their nanotechonology (BIND study). They also have about 30 other trials going on. Travel to Arizona would be required..Comments (0) -
Information regarding Octreotide
Here is some additional information on Octreotide. The first two articles offer some hopeful conclusions and the third article provides a good summary of what Octreotide is and what it does:http://www.ncbi.nlm.nih.gov/pubmed/12483273
http://www.ncbi.nlm.nih.gov/pubmed/7768398
http://www.chemocare.com/bio/octreotide.asp
I also found this article during my search and feel that it contains some additional encouraging info that also supports the nutritional path that Bruce is on (mention of food-based polyphenols)…
http://www.cancernetwork.com/gastrointestinal-stromal-tumor/content/article/1549113/1659379
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Information regarding Sutent
This is one of the "targeted agents" that Dr. Marks indicated was identified as working with Bruce's cancer (from lab work done in AZ on Bruce's tissue).Comments (0) -
Information regarding Nexovar
Nexovar is the trade name for sorafenib. It’s antiangiogenic therapy, which means that it keeps the blood vessels from growing that the tumor needs to survive. As I remember, it showed up in some of the initial research that we did as a promising therapy (i.e. some people were having luck with it). Not sure if it is considered a “standard chemo.” It was initially developed for kidney cancer. The paper that I read also said that it inhibits/blocks growth factors. Here is a link to a chemocare page about sorafenib which may contain good info about other drugs.
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Other Resources
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The Fungus Connection
Lots of information regarding the connection between Fungus (yeast and molds) and Cancer.
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Recommended Reading
These are the books that have helped with developing Bruce's overarching health plan.
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TargetNow - Caris Life Sciences
Caris Life Sciences'™ molecular profiling test, Caris Target Now™, examines the genetic and molecular changes unique to a patient's tumor so that treatment options may be matched to the tumor's molecular profile. Caris Target Now helps patients and their treating physicians create a cancer treatment plan based on the tumor tested. By comparing the tumor's information with data from published clinical studies by thousands of the world's leading cancer researchers, Caris can help determine which treatments are likely to be most effective and, just as important, which treatments are likely to be ineffective.www.targetnow.comwww.carislifesciences.com/oncology-target-now
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Tgen
The Translational Genomics Research Institute (TGen), a non-profit 501(c)(3) organization, is focused on developing earlier diagnoses and smarter treatments. Translational genomics research employs innovative advances arising from the Human Genome Project by applying them to the development of diagnostics, prognostics, and therapies for cancer, neurological disorders, diabetes and other complex diseases. TGen's research is based on personalized medicine and the institute plans to accomplish its goals through robust and disease-focused research. TGen headquarters